BRD-5529
BRD-5529 is a selective, cell-permeable CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction inhibitor (IC50 of 8.6 μM). BRD-5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation and activation of CARD9, and demonstrates cellular activity and selectivity in CARD9-dependent pathways.
Product Specifications
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months
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