Rivulariapeptolides 1121
Rivulariapeptolides 1121 is a high potent and selective serine protease inhibitor with IC50 values of 35.52 nM, 13.24 nM and 48.05 nM for chymotrypsin, elastase and proteinase K, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/rivulariapeptolides-1121.html
Solubility
10 mM in DMSO
Smiles
CCCC(N1[C@H](C(N[C@H](C(N[C@H](C(N/C(C(N[C@H]2CC[C@@H](O)[N@@]3C2=O)=O)=C\C)=O)[C@@H](C)OC([C@H](C(C)C)NC([C@H](CC4=CC=C(O)C=C4)N(C([C@@H]3CC(C)C)=O)C)=O)=O)=O)[C@H](OC([C@@H]5CCCN5C(CCC)=O)=O)C)=O)CCC1)=O
Molecular Formula
C56H83N9O15
Molecular Weight
1122.31
References & Citations
[1]Raphael Reher, et al. Native metabolomics identifies the rivulariapeptolide family of protease inhibitors. Nat Commun. 2022 Aug 8;13 (1) :4619.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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