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(2R/S)-6-PNG

Product Specifications

UNSPSC Description

(2R/S)-6-PNG (6-Prenylnaringenin) is a potent and reversible Cav3.2 T-type Ca2+ channels (T-channels) blocker. (2R/S)-6-PNG can penetrate the blood-brain barrier (BBB). (2R/S)-6-PNG suppresses neuropathic and visceral pain in mice[1].

Target Antigen

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/2r-s-6-png.html

Purity

99.88

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1CC(C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)\C)C(O)=C13

Molecular Weight

340.37

References & Citations

[1]Fumiko Sekiguchi, et al. Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice. Neuropharmacology

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-115681/2R-S-6-PNG-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-115681/2R-S-6-PNG-SDS-MedChemExpress.pdf

Clinical Information

Phase 1

CAS Number

68682-01-9

Available Sizes

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