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Abyssinone V

Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V can be isolated from the stem bark of Erythrina melanacantha. Abyssinone V possesses good pharmacodynamics properties. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity[1][2].

Product Specifications

CAS Number

77263-11-7

UNSPSC

12352005

Target

ATP Synthase; DNA/RNA Synthesis; HSV

Type

Natural Products

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/abyssinone-v.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C(O[C@H](C(C=C2C/C=C(C)/C)=CC(C/C=C(C)/C)=C2O)C1)=CC(O)=C3)=C3O

Molecular Formula

C25H28O5

Molecular Weight

408.49

References & Citations

[1]Koch K, et al. Abyssinone V, a prenylated flavonoid isolated from the stem bark of Erythrina melanacantha increases oxidative stress and decreases stress resistance in Caenorhabditis elegans. J Pharm Pharmacol. 2019 Jun;71 (6) :1007-1016. |[2]Kwofie SK, et al. Identification of novel potential inhibitors of varicella-zoster virus thymidine kinase from ethnopharmacologic relevant plants through an in-silico approach. J Biomol Struct Dyn. 2022;40 (23) :12932-12947.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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