FGIN 1-27
FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a Ki of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB) . FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions[1].
Product Specifications
CAS Number
142720-24-9
UNSPSC
12352005
Hazard Statement
H315, H319
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fgin-1-27.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(CCCCCC)CCCCCC)CC1=C(C2=CC=C(F)C=C2)NC3=C1C=CC=C3
Molecular Formula
C28H37FN2O
Molecular Weight
436.60
Precautions
H315, H319
References & Citations
[1]Michelle L James, et al. Development of ligands for the peripheral benzodiazepine receptor. Curr Med Chem. 2006;13 (17) :1991-2001.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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