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FGIN 1-27

FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a Ki of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB) . FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions[1].

Product Specifications

CAS Number

142720-24-9

UNSPSC

12352005

Hazard Statement

H315, H319

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fgin-1-27.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N(CCCCCC)CCCCCC)CC1=C(C2=CC=C(F)C=C2)NC3=C1C=CC=C3

Molecular Formula

C28H37FN2O

Molecular Weight

436.60

Precautions

H315, H319

References & Citations

[1]Michelle L James, et al. Development of ligands for the peripheral benzodiazepine receptor. Curr Med Chem. 2006;13 (17) :1991-2001.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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