Diphenylacetic acid

Diphenylacetic acid (Diphenylmethane-α-carboxylic Acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diphenylacetic acid can be used as a reagent in the kinetic resolution of racemic 2-hydroxy-y-butyrolactones by asymmetric esterification in the presence of pivalic anhydride and chiral acyl-transfer catalyst. Diphenylacetic acid can act as a catalyst to synthesize 2-allyl-3-oxazolin-5-one derivatives via Rh-catalyzed coupling reaction of azlactones and alkynes followed by aza-Cope rearrangement[1][2][3][4].

Product Specifications

CAS Number

[117-34-0]

Product Name Alternative

Diphenylmethane-α-carboxylic Acid

UNSPSC

12352200

Hazard Statement

H302, H319, H412

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/diphenylacetic-acid.html

Purity

99.96

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(O)C(C1=CC=CC=C1)C2=CC=CC=C2

Molecular Formula

C14H12O2

Molecular Weight

212.25

Precautions

H302, H319, H412

References & Citations

[4]Kuang, J., et al., (2017) . Rhodium-Catalyzed Regioselective Domino Azlactone-Alkyne Coupling/Aza-Cope Rearrangement: Facile Access to 2-Allyl-3-oxazolin-5-ones and Trisubstituted Pyridines. Angewandte Chemie (International ed. in English), 56 (29), 8422–8425.|[1]Bergmeyer H U, et al. Biochemical reagents[M]//Methods of Enzymatic Analysis. Academic Press, 1965: 967-1037.|[2]Nakata, K., et al., (2013) . Kinetic resolution of racemic 2-hydroxy-γ-butyrolactones by asymmetric esterification using diphenylacetic acid with pivalic anhydride and a chiral acyl-transfer catalyst. Organic letters, 15 (6), 1170–1173. |[3]Rajkumar, S., et al., (2015) . Ru (II) -Catalyzed β-Carboline Directed C-H Arylation and Isolation of Its Cycloruthenated Intermediates. The Journal of organic chemistry, 80 (11), 5532–5545.