JC124
JC124 is a specific NLRP3 inflammasome inhibitor. JC124 has anti-inflammatory and neuroprotective effects[1].
Product Specifications
CAS Number
[1638611-48-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jc124.html
Purity
99.72
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(Cl)=CC=C1OC)NCCC2=CC=C(C=C2)S(=O)(NC)=O
Molecular Formula
C17H19ClN2O4S
Molecular Weight
382.86
Precautions
H302, H315, H319
References & Citations
[1]Ram Kuwar, et al. A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury. J Neuroinflammation. 2019 Apr 11;16 (1) :81.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3
Available Sizes
Curated Selection
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