JC124
Product Specifications
UNSPSC Description
JC124 is a specific NLRP3 inflammasome inhibitor. JC124 has anti-inflammatory and neuroprotective effects[1].
Target Antigen
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jc124.html
Purity
97.13
Solubility
DMSO : 250 mg/mL (ultrasonic;adjust pH to 3 with HCl)
Smiles
O=C(C1=CC(Cl)=CC=C1OC)NCCC2=CC=C(C=C2)S(=O)(NC)=O
Molecular Weight
382.86
References & Citations
[1]Ram Kuwar, et al. A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury. J Neuroinflammation. 2019 Apr 11;16(1):81.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120007/JC124-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120007/JC124-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1638611-48-9
Available Sizes
Curated Selection
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