AaHI

AaHI is a neurotoxin that can be obtained from the venom of the North African scorpion Androctonus australis hector. AaHI can be used as a tool for the development of active substances with toxin-neutralizing capabilities[1].

O=C([C@@H](N)CCCCN)N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N3[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H]4CO)=O)=O)CO)=O)CO)=O)=O)=O)CC(N)=O)=O)CCCCN)=O)CCCCN)=O)CSSC[C@H](NC5=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N6[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N7[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]8CCCCN)=O)CCCNC(N)=N)=O)CO)=O)[C@@H](C)O)=O)CC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)CCC7)=O)C(C)C)=O)CC(N)=O)=O)CC(O)=O)=O)CCC6)=O)CC(C)C)=O)CC(O)=O)=O)CCCCN)=O)=O)CC(C)C)=O)=O)CC(O)=O)=O)CSSC[C@H](NC9=O)C(N[C@H]5CC%10=CNC%11=CC=CC=C%10%11)=O)=O)CCC3)=O)CCC2)=O)C(C)C)=O)CSSC[C@H](NC4=O)C(NC(C(NC(C(NC(C(NC(C(N%12C(C(NC(C(NCC(NC(C(NC9C)=O)CC(C)C)=O)=O)CO)=O)CCC%12)=O)C(C)C)=O)CC(C)C)=O)CC%13=CC=CC=C%13)=O)CO)=O)=O)CC%14=CNC=N%14)=O)CC%15=CC=C(O)C=C%15)=O)C(C)C)=O)CSSC[C@H](NC8=O)C(N[C@H](C(O)=O)[C@@H](C)O)=O)=O)CC(N)=O)=O)CC(N)=O)=O)CCC1)=O)CC%16=CC=C(O)C=C%16)=O)C(C)C)=O)[C@H](CC)C)=O)CC%17=CC=C(O)C=C%17)=O)=O)CC(O)=O)=O)CCCNC(N)=N

[1]Devaux C, et al. Construction and functional evaluation of a single-chain antibody fragment that neutralizes toxin AahI from the venom of the scorpion Androctonus australis hector. Eur J Biochem. 2001 Feb;268(3):694-702.