HEK293/Human GLP-1R Stable Cell Line (Medium Expression)
HEK293/Human GLP-1R Stable Cell Line (Medium Expression) is expressed from Human HEK293.
Product Specifications
Background
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.
Host
HEK293
Origin Species
Human
Target
GLP1R
Applications
• Useful for cell-based GLP-1R binding assay • Screen for human GLP-1R agonists based on cAMP accumulation assay
Format
Liquid
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
Frozen in liquid nitrogen
Package Size
1Vial*2
Host or Source
HEK293
Species
Human
Curated Selection
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