QDPR-IN-1
QDPR-IN-1 (Compound 9b) is a potent QDPR inhibitor with an IC50 of 0.72 μM[1].
Product Specifications
CAS Number
29415-71-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dihydrofolate reductase (DHFR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/qdpr-in-1.html
Purity
99.28
Solubility
DMSO : 3.12 mg/mL (ultrasonic; adjust pH to 4 with 1 M HCl)
Smiles
O=C1NNC(C2=CC(N(CC)CC)=CC=C12)=O
Molecular Formula
C12H15N3O2
Molecular Weight
233.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Hara S, et al. Inhibition of QDPR synergistically modulates intracellular tetrahydrobiopterin profiles in cooperation with methotrexate. Biochem Biophys Res Commun. 2024 Jul 12;717:150059.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TP303798 20 µg
Dystrobrevin beta (DTNB) (NM_183361) Human Recombinant Protein
Sign In for Pricing
View Details 
BNUB1999-100 1x 100 µL
Human Kappa Light Chain (B-Cell Marker) (IGKC/1999R), 0.2mg/mL
Sign In for Pricing
View Details 
