P, p'-DDE-d8
P, p'-DDE-d8 is the deuterium labeled p, p'-DDE[1]. p, p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[2].
Product Specifications
Product Name Alternative
4,4'-DDE-d8; p, p'-Dichlorodiphenyldichloroethylene-d8
UNSPSC
12352005
Target
Androgen Receptor; Drug Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Purity
99
Solubility
10 mM in DMSO
Smiles
Cl/C(Cl)=C(C1=C([2H])C([2H])=C(C([2H])=C1[2H])Cl)/C2=C([2H])C([2H])=C(C([2H])=C2[2H])Cl
Molecular Formula
C14D8Cl4
Molecular Weight
326.07
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1986S/p-p-DDE-d8-SDS-MedChemExpress.pdf
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
CAS Number
[93952-19-3]
Available Sizes
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