Human Beta-2-Glycoprotein 1

<strong>Human Beta-2-Glycoprotein 1</strong>_x000D_ <strong>Catalog number:</strong> B2016568_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg _x000D_ <strong>Molecular Weight or Concentration:</strong> 32700_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Human Beta-2-Glycoprotein 1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong> _x000D_ 1: Reshetnyak TM, Cheldieva FA, Cherkasova MV, Glukhova SI, Lila AM, Nasonov EL. Antibodies to Domain I β(2)-Glycoprotein 1 in Patients with Antiphospholipid Syndrome and Systemic Lupus Erythematosus Dokl Biochem Biophys. 2023 Aug;511(1):219-226. _x000D_ 2: Sciascia S, Radin M, Cecchi I, Fenoglio R, De Marchi A, Besso L, Baldovino S, Rossi D, Miraglia P, Rubini E, Roccatello D. Anti-beta-2-glycoprotein I domain 1 identifies antiphospholipid antibodies-related injuries in patients with concomitant lupus nephritis J Nephrol. 2020 Aug;33(4):757-762. _x000D_ 3: Chighizola CB, Pregnolato F, Andrade D, Tektonidou M, Pengo V, Ruiz-Irastorza G, Belmont HM, Gerosa M, Fortin P, Branch DW, Andreoli L, Petri MA, Cervera R, Knight JS, Willis R, Efthymiou M, Cohen H, Erkan D, Bertolaccini ML; Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION). Fluctuation of Anti-Domain 1 and Anti-β(2) -Glycoprotein I Antibody Titers Over Time in Patients With Persistently Positive Antiphospholipid Antibodies Arthritis Rheumatol. 2023 Jun;75(6):984-995. _x000D_ 4: Fierro JJ, Velásquez M, Cadavid AP, de Leeuw K. Effects of anti-beta 2-glycoprotein 1 antibodies and its association with pregnancy-related morbidity in antiphospholipid syndrome Am J Reprod Immunol. 2022 Jan;87(1):e13509. _x000D_ 5: Committee on Practice Bulletins—Obstetrics, American College of Obstetricians and Gynecologists. Practice Bulletin No. 132: Antiphospholipid syndrome Obstet Gynecol. 2012 Dec;120(6):1514-21. _x000D_ 6: Kumar S, Wulf J 2nd, Basore K, Pozzi N. Structural analyses of β(2)-glycoprotein I: is there a circular conformation? J Thromb Haemost. 2023 Dec;21(12):3511-3521. _x000D_ 7: Lee JS, Lee EJ, Yeom J, Oh JS, Hong S, Lee CK, Yoo B, Kim K, Kim YG. Urine β-2-glycoprotein 1 as a biomarker for diagnosis of systemic lupus erythematosus Lupus. 2021 Jul;30(8):1306-1313. _x000D_ 8: de Groot PG, Meijers JC. β(2) -Glycoprotein I: evolution, structure and function J Thromb Haemost. 2011 Jul;9(7):1275-84. _x000D_ 9: Szabó G, Debreceni IB, Tarr T, Soltész P, Østerud B, Kappelmayer J. Anti-β(2)-glycoprotein I autoantibodies influence thrombin generation parameters via various mechanisms Thromb Res. 2021 Jan;197:124-131. _x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32001534">10: Pignatelli P, Ettorre E, Menichelli D, Pani A, Violi F, Pastori D. Seronegative antiphospholipid syndrome: refining the value of "non-criteria" antibodies for diagnosis and clinical management Haematologica. 2020 Mar;105(3):562-572. </a>_x000D_ <br><strong>Products Related to Human Beta-2-Glycoprotein 1 can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>