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CD162/PSGL-1, Human (HEK293, His-Fc)

CD162/PSGL-1 Protein is a sialomucin expressed on leukocytes, which through high affinity, calcium-dependent interactions with E- and P-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation[1]. CD162/PSGL-1 Protein, Human (HEK293, His-Fc) is the recombinant human-derived CD162/PSGL-1 protein, expressed by HEK293 , with C-His, C-hFc labeled tag.

Product Specifications

Product Name Alternative

CD162/PSGL-1 Protein, Human (HEK293, His-Fc), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/cd162-psgl-1-protein-human-hek293-his-fc.html

Molecular Formula

6404 (Gene_ID) AAC50061.1 (L18-V295) (Accession)

Molecular Weight

Approximately 110-120 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]T Hirata, et al. P-Selectin glycoprotein ligand 1 (PSGL-1) is a physiological ligand for E-selectin in mediating T helper 1 lymphocyte migration. J Exp Med. 2000 Dec 4;192 (11) :1669-76.|[2]Silvere D Zaongo, et al. PSGL-1, a Strategic Biomarker for Pathological Conditions in HIV Infection: A Hypothesis Review. Viruses. 2023 Oct 31;15 (11) :2197.

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

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