CSNK2-IN-2
Product Specifications
UNSPSC Description
CSNK2-IN-2 (compound 2) is an orally active CSNK2 inhibitor. CSNK2-IN-2 has an IC50 of 29 μM against CLK11. CSNK2-IN-2 has a half-life of 2.5 h and an AUC of 10,100 h × nM. CSNK2-IN-2 can be used in antiviral studies[1].
Target Antigen
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Stem Cell/Wnt
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/csnk2-in-2.html
Smiles
CCC(NC1=CC(NC2=NC3=C(C#N)C=NN3C(NC4CC4)=C2)=C(F)C=C1N5C[C@@H](NC)CCC5)=O
Molecular Weight
491.56
References & Citations
[1]Ong HW, et al. Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2. Molecules. 2024 Sep 2;29(17):4158.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168595/CSNK2-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168595/
Clinical Information
No Development Reported
Curated Selection
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