SKF 95601
SKF 95601 is a modulator of small conductive Ca2+-activated K+ channels with anti-atrial fibrillation (AF) activity. SKF 95601 may play a role in inhibiting atrial fibrillation by affecting the interaction between intracellular Ca2+ concentration and membrane potential. SKF 95601 has become a potential inhibitory target against atrial fibrillation due to its significant expression in various species, especially human atria[1].
Product Specifications
CAS Number
103949-62-8
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/skf-95601.html
Smiles
COC1=CC=C2N=C(S(CC3=NC=CC(N4CCOCC4)=C3Cl)=O)NC2=C1
Molecular Formula
C18H19ClN4O3S
Molecular Weight
406.89
References & Citations
[1]Modulation of SK Channels: Insight Into Therapeutics of Atrial Fibrillation
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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