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SKF 95601

SKF 95601 is a modulator of small conductive Ca2+-activated K+ channels with anti-atrial fibrillation (AF) activity. SKF 95601 may play a role in inhibiting atrial fibrillation by affecting the interaction between intracellular Ca2+ concentration and membrane potential. SKF 95601 has become a potential inhibitory target against atrial fibrillation due to its significant expression in various species, especially human atria[1].

Product Specifications

CAS Number

103949-62-8

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/skf-95601.html

Smiles

COC1=CC=C2N=C(S(CC3=NC=CC(N4CCOCC4)=C3Cl)=O)NC2=C1

Molecular Formula

C18H19ClN4O3S

Molecular Weight

406.89

References & Citations

[1]Modulation of SK Channels: Insight Into Therapeutics of Atrial Fibrillation

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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