CCT369260
Product Specifications
UNSPSC Description
CCT369260 (compound 1) is an orally avtive B-cell lymphoma 6 (BCL6) inhibitor with anti-tumor activity. CCT369260 (compound 1) exhibits an IC50 of 520 nM[1].
Target Antigen
Bcl-2 Family; Molecular Glues
Type
Reference compound
Related Pathways
Apoptosis;PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl6-in-3.html
Purity
99.77
Solubility
DMSO : 300 mg/mL (ultrasonic)
Smiles
O=C1N(CCC(C)(O)C)C2=CC(NC3=NC(N4C[C@@H](C)C(F)(F)[C@@H](C)C4)=NC=C3Cl)=CC=C2N1C
Molecular Weight
508.99
References & Citations
[1]Benjamin R Bellenie, et al. Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders. J Med Chem. 2020 Apr 23;63(8):4047-4068.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129188/CCT369260-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129188/CCT369260-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2647503-57-7
Available Sizes
Curated Selection
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