ALDH1A1-IN-4

ALDH1A1-IN-4 (compound A1) is a potent inhibitor of aldehyde dehydrogenase (ALDH) A1, with IC50 value of 0.32 μM. ALDH1A1-IN-4 plays an important role in cancer research[1].

Product Specifications

CAS Number

[23982-86-7]

UNSPSC

12352005

Target

Aldehyde Dehydrogenase (ALDH)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aldh1a1-in-4.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C2=NC3=CC=CC=C3N2CC4=CC=CC=C4)C=C1

Molecular Formula

C20H15ClN2

Molecular Weight

318.80

References & Citations

[1]Gera Narendra, et al. Scaffold hopping based designing of selective ALDH1A1 inhibitors to overcome cyclophosphamide resistance: synthesis and biological evaluation. RSC Med Chem. 2023 Nov 30;15 (1) :309-321.