PSB-16131
PSB-16131 is a potent inhibitor of human NTPDase2, showing non-competitive inhibition with an IC50 of 539 nM. PSB-16131 can be used in the study of inflammation, neurodegenerative diseases and cancer[1].
Product Specifications
CAS Number
[1213268-80-4]
UNSPSC
12352005
Target
NTPDase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/psb-16131.html
Purity
99.94
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=S(C1=CC(NC2=CC3=CC=CC=C3C4=CC=CC=C42)=C(C(C5=C6C=CC=C5)=O)C(C6=O)=C1N)(O[Na])=O
Molecular Formula
C28H17N2NaO5S
Molecular Weight
516.50
References & Citations
[1]Development of Anthraquinone Derivatives as Ectonucleoside Triphosphate Diphosphohydrolase (NTPDase) Inhibitors With Selectivity for NTPDase2 and NTPDase3
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NTPDase2
Available Sizes
Curated Selection
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