Mal-PEG3-VCP-NB
Mal-PEG3-VCP-NB (Compund 25c) is a degradable ADC linker containing a maleimide group, 3-unit PEG and VCP NB[1].
Product Specifications
CAS Number
1345681-77-7
UNSPSC
12352203
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg3-vcp-nb.html
Smiles
O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCOCCOCCN3C(C=CC3=O)=O)=O)=O)=O)=O
Molecular Formula
C36H45N7O14
Molecular Weight
799.78
References & Citations
[1]Beusker P H, et al. Novel conjugates of CC-1065 analogs and bifunctional linkers[P]. 2011-10-27.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Protease Cleavable Linker
Frequently Asked Questions
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