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Doxorubicinone (Standard)

Doxorubicinone (Standard) is the analytical standard of Doxorubicinone. This product is intended for research and analytical applications. Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

Product Specifications

CAS Number

24385-10-2

Product Name Alternative

Adriamycin aglycone (Standard) ; Adriamycinone (Standard)

UNSPSC

12352005

Target

Endogenous Metabolite; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/doxorubicinone-standard.html

Smiles

OC1=C(C2=C(C(C3=O)=C1C(C4=CC=CC(OC)=C34)=O)O)C[C@](O)(C[C@@H]2O)C(CO)=O

Molecular Formula

C21H18O9

Molecular Weight

414.36

References & Citations

[1]M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55 (5) :488-96.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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