Tyrosylhistidine

Tyrosylhistidine is a dipeptide consisting of tyrosine and histidine (Tyr-His) . Tyrosylhistidine is an orally active antihypertensive peptide. Tyrosylhistidine reduces blood pressure in mice in a model of spontaneous hypertension[1].

Product Specifications

CAS Number

[3788-44-1]

UNSPSC

12352209

Hazard Statement

H315-H319

Target

Angiotensin-converting Enzyme (ACE)

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/tyrosylhistidine.html

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1C[C@H](N)C(N[C@H](C(O)=O)CC2=CN=CN2)=O

Molecular Formula

C15H18N4O4

Molecular Weight

318.33

Precautions

P264-P280-P302+P352-P305+P351+P338-P362+P364

References & Citations

[1]Suetsuna K, et al. Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats. J Nutr Biochem. 2004 May;15 (5) :267-72.