Lactate Dehydrogenase 5

<strong>Lactate Dehydrogenase 5</strong>_x000D_ <strong>Catalog number:</strong> B2016908_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 U_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Suspension_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Lactate dehydrogenase 5, LDH-5, LD-5 Isoenzyme, LDH-5 Isoenzyme, 4M Isoenzyme_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lemire J, Auger C, Mailloux R, Appanna VD. Mitochondrial lactate metabolism is involved in antioxidative defense in human astrocytoma cells J Neurosci Res. 2014 Apr;92(4):464-75._x000D_ 2: Wang Y, Wei L, Wei D, Li X, Xu L, Wei L. Testis-Specific Lactate Dehydrogenase (LDH-C4) in Skeletal Muscle Enhances a Pika's Sprint-Running Capacity in Hypoxic Environment Int J Environ Res Public Health. 2015 Aug 7;12(8):9218-36._x000D_ 3: Feng Y, Xiong Y, Qiao T, Li X, Jia L, Han Y. Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy Cancer Med. 2018 Dec;7(12):6124-6136._x000D_ 4: Zhang SL, He Y, Tam KY. Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH)5 inhibitors Drug Discov Today. 2018 Jul;23(7):1407-1415._x000D_ 5: Sharma D, Singh M, Rani R. Role of LDH in tumor glycolysis: Regulation of LDHA by small molecules for cancer therapeutics Semin Cancer Biol. 2022 Dec;87:184-195._x000D_ 6: Read JA, Winter VJ, Eszes CM, Sessions RB, Brady RL. Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase Proteins. 2001 May 1;43(2):175-85._x000D_ 7: Khan F, Lin Y, Ali H, Pang L, Dunterman M, Hsu WH, Frenis K, Grant Rowe R, Wainwright DA, McCortney K, Billingham LK, Miska J, Horbinski C, Lesniak MS, Chen P. Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression Nat Commun. 2024 Mar 5;15(1):1987._x000D_ 8: Urbańska K, Orzechowski A. Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells Int J Mol Sci. 2019 Apr 27;20(9):2085._x000D_ 9: Xu K, Yin N, Peng M, Stamatiades EG, Shyu A, Li P, Zhang X, Do MH, Wang Z, Capistrano KJ, Chou C, Levine AG, Rudensky AY, Li MO. Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity Science. 2021 Jan 22;371(6527):405-410._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/36064857">10: Feng T, Zhao X, Gu P, Yang W, Wang C, Guo Q, Long Q, Liu Q, Cheng Y, Li J, Cheung CKY, Wu D, Kong X, Xu Y, Ye D, Hua S, Loomes K, Xu A, Hui X. Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2 Nat Commun. 2022 Sep 5;13(1):5208. </a>_x000D_ _x000D_ <strong>Products Related to Lactate Dehydrogenase 5 can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>