Pan-KRAS-IN-15
Pan-KRAS-IN-15 (compound 58) is a pan-KRAS inhibitor. pan-KRAS-IN-15 can be used in pancreatic cancer research[1].
Product Specifications
CAS Number
3034052-52-0
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pan-kras-in-15.html
Solubility
10 mM in DMSO
Smiles
CC#CC1=C2C(N3C[C@@H](CC4)N[C@@H]4C3)=NC(OC[C@@]56CCCN5C[C@@H](C6)F)=NC2=C(C(C7=CC(O)=CC8=C7C(CC)=C(C=C8)F)=N1)F
Molecular Formula
C36H37F3N6O2
Molecular Weight
642.71
References & Citations
[1]Ying Lei, et al. Kras mutant protein inhibitor, preparation method therefor, and use thereof.WO2024061333A1.2023-09-21
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
Frequently Asked Questions
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