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Pan-KRAS-IN-15

Pan-KRAS-IN-15 (compound 58) is a pan-KRAS inhibitor. pan-KRAS-IN-15 can be used in pancreatic cancer research[1].

Product Specifications

CAS Number

3034052-52-0

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pan-kras-in-15.html

Solubility

10 mM in DMSO

Smiles

CC#CC1=C2C(N3C[C@@H](CC4)N[C@@H]4C3)=NC(OC[C@@]56CCCN5C[C@@H](C6)F)=NC2=C(C(C7=CC(O)=CC8=C7C(CC)=C(C=C8)F)=N1)F

Molecular Formula

C36H37F3N6O2

Molecular Weight

642.71

References & Citations

[1]Ying Lei, et al. Kras mutant protein inhibitor, preparation method therefor, and use thereof.WO2024061333A1.2023-09-21

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

Frequently Asked Questions

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