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NPE-caged-HPTS (sodium)

NPE-caged-HPTS sodium is a caged fluorophore that fluoresces upon uncaged fluorophore release, releasing the free highly polar fluorophore HPTS (Exc=470/40 nm, Em=525/50 nm) . HPTS releases the fluorophore rapidly and uniformly, allowing for measurement of diffusion within tissues, with a diffusion coefficient of μm2s-1, similar to that of synaptic L-glutamate[1].

Product Specifications

CAS Number

223759-19-1

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/npe-caged-hpts-sodium.html

Smiles

O=S(C(C1=CC=C2C3=C14)=CC(S(=O)(O[Na])=O)=C4C=CC3=C(S(=O)(O[Na])=O)C=C2OC(C)C5=C(C=CC=C5)[N+]([O-])=O)(O[Na])=O

Molecular Formula

C24H14NNa3O12S3

Molecular Weight

673.53

References & Citations

[1]Palma-Cerda F, Papageorgiou G, Barbour B, et al. Photolysis of a Caged, Fast-Equilibrating Glutamate Receptor Antagonist, MNI-Caged γ-D-Glutamyl-Glycine, to Investigate Transmitter Dynamics and Receptor Properties at Glutamatergic Synapses[J]. Frontiers in Cellular Neuroscience, 2018, 12: 465.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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