Aprutumab

Aprutumab (BAY 1179470) is a fully human FGFR2 monoclonal antibody, which binds to the FGFR2 isoforms FGFR2-IIIb and FGFR2-IIIc. Aprutumab has the potential for solid tumors research[1].

Product Specifications

CAS Number

[1634620-63-5]

Product Name Alternative

BAY 1179470

UNSPSC

12352203

Target

FGFR

Type

Inhibitory Antibodies

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aprutumab.html

Purity

99.00

Solubility

H2O

Smiles

[Aprutumab]

Molecular Weight

(144.6 kDa)

References & Citations

[1]Anette Sommer, et al. Preclinical Efficacy of the Auristatin-Based Antibody–Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors. Cancer Res (2016) 76 (21) : 6331–6339.