MK8722
MK8722 is a potent and systemic pan-AMPK activator.
Product Specifications
CAS Number
[1394371-71-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/MK8722.html
Purity
99.82
Solubility
DMSO : 31.25 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@]([C@]2([H])OC1)([H])OC[C@H]2OC3=NC4=NC(C(C=C5)=CC=C5C6=CC=CC=C6)=C(Cl)C=C4N3
Molecular Formula
C24H20ClN3O4
Molecular Weight
449.89
Precautions
H302, H315, H319, H335
References & Citations
[1]Myers RW, et al. Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiachypertrophy. Science. 2017 Aug 4;357 (6350) :507-511.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPK
Available Sizes
Curated Selection
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