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MK8722

MK8722 is a potent and systemic pan-AMPK activator.

Product Specifications

CAS Number

[1394371-71-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

AMPK

Type

Reference compound

Related Pathways

Epigenetics; PI3K/Akt/mTOR

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/MK8722.html

Purity

99.82

Solubility

DMSO : 31.25 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@]([C@]2([H])OC1)([H])OC[C@H]2OC3=NC4=NC(C(C=C5)=CC=C5C6=CC=CC=C6)=C(Cl)C=C4N3

Molecular Formula

C24H20ClN3O4

Molecular Weight

449.89

Precautions

H302, H315, H319, H335

References & Citations

[1]Myers RW, et al. Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiachypertrophy. Science. 2017 Aug 4;357 (6350) :507-511.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AMPK

Available Sizes

Curated Selection

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