Glychionide A
Product Specifications
UNSPSC Description
Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer[1][2].
Target Antigen
Apoptosis; Autophagy
Type
Natural Products
Related Pathways
Apoptosis;Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glychionide-a.html
Purity
99.47
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C(OC(C2=CC=CC=C2)=C1)=C3O)=C(C=C3O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)C(O)=O)O
Molecular Weight
446.36
References & Citations
[1]Li JR, et, al. Two new compounds from Glycyrrhiza glabra. J Asian Nat Prod Res. 2005 Aug;7(4):677-80.|[2]Yu L, et, al. Antitumor Effects of Glychionide-A Flavonoid in Human Pancreatic Carcinoma Cells Are Mediated by Activation of Apoptotic and Autophagic Pathways, Cell Cycle Arrest, and Disruption of Mitochondrial Membrane Potential. Med Sci Monit. 2019 Feb 3;25:962-969.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N8034/Glychionide-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N8034/Glychionide-A-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
119152-50-0
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