D-Pro-Phe-Arg-Chloromethylketone
D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation[1].
Product Specifications
CAS Number
[88546-74-1]
UNSPSC
12352209
Target
Factor Xa; Kallikrein
Type
Peptides
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/d-pro-phe-arg-chloromethylketone.html
Purity
99.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1CCCN1)N[C@H](C(N[C@H](C(CCl)=O)CCCNC(N)=N)=O)CC2=CC=CC=C2
Molecular Formula
C21H31ClN6O3
Molecular Weight
450.96
References & Citations
[1]Katrin F Nickel, et al. Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases. Arterioscler Thromb Vasc Biol. 2017 Jan;37 (1) :13-20.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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