GP130 receptor agonist-1
GP130 receptor agonist-1 is a potent, brain-penetrant and orally active GP130 receptor agonist. GP130 receptor agonist-1 has a neuroprotective effect on NMDA-induced neurotoxicity[1].
Product Specifications
CAS Number
[339303-87-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gp130-receptor-agonist-1.html
Concentration
10mM
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC1=CC=C(C=C1)NC2=NC(C3=CC=CC=C3)=CS2
Molecular Formula
C15H11FN2S
Molecular Weight
270.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Mohammad Parvez Alam, et al. A Small Molecule Mimetic of the Humanin Peptide as a Candidate for Modulating NMDA-Induced Neurotoxicity. ACS Chem Neurosci. 2018 Mar 21;9 (3) :462-468.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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