CGP 44 645
CGP 44 645 is the methanol metabolite of Letrozole (HY-14248) and is a molecular indicator for evaluating its metabolic kinetics in microsomes in vitro. Levels of CGP 44 645 in rat liver microsomes may be sex-specific[1].
Product Specifications
CAS Number
[134521-16-7]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cgp-44-645.html
Purity
98.13
Solubility
DMSO : ≥ 200 mg/mL
Smiles
OC(C1=CC=C(C=C1)C#N)C2=CC=C(C=C2)C#N
Molecular Formula
C15H10N2O
Molecular Weight
234.26
Precautions
H315, H319, H335
References & Citations
[1]Tao X, Piao H, Canney DJ, Borenstein MR, Nnane IP. Biotransformation of letrozole in rat liver microsomes: effects of gender and tamoxifen. J Pharm Biomed Anal. 2007 Feb 19;43 (3) :1078-85.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
245658-ML650 100 µL
EIF4EBP1 (Eukaryotic Translation Initiation Factor 4E Binding Protein 1, 4E-BP1, 4EBP1, BP-1, MGC4316, PHAS-I) (MaxLight 650)
Ask
View Details