Glutaminyl Cyclase Inhibitor 1
Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM.
Product Specifications
CAS Number
2110449-60-8
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Glutaminyl_Cyclase_Inhibitor_1.html
Purity
99.61
Solubility
DMSO : 83.33 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)
Smiles
FC1=CC=CC(C2=CC(OC)=C(OC)C=C2)=C1NCCCN3C=C(C)N=C3
Molecular Formula
C21H24FN3O2
Molecular Weight
369.43
References & Citations
[1]Li M, et al. Synthesis and Evaluation of Diphenyl Conjugated Imidazole Derivatives as Potential Glutaminyl Cyclase Inhibitors for Treatment of Alzheimer's Disease. J Med Chem. 2017 Aug 10;60 (15) :6664-6677.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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