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Glutaminyl Cyclase Inhibitor 1

Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM.

Product Specifications

CAS Number

2110449-60-8

UNSPSC

12352005

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Glutaminyl_Cyclase_Inhibitor_1.html

Purity

99.61

Solubility

DMSO : 83.33 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

Smiles

FC1=CC=CC(C2=CC(OC)=C(OC)C=C2)=C1NCCCN3C=C(C)N=C3

Molecular Formula

C21H24FN3O2

Molecular Weight

369.43

References & Citations

[1]Li M, et al. Synthesis and Evaluation of Diphenyl Conjugated Imidazole Derivatives as Potential Glutaminyl Cyclase Inhibitors for Treatment of Alzheimer's Disease. J Med Chem. 2017 Aug 10;60 (15) :6664-6677.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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