Eglin c (60-63) -methyl ester

<strong>Eglin c (60-63)-methyl ester</strong>_x000D_ <strong>Catalog number:</strong> B2019069_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 445.52 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> Eglin c (60-63)-methyl ester_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Tsuboi S, Nakabayashi K, Matsumoto Y, Teno N, Tsuda Y, Okada Y, Nagamatsu Y, Yamamoto J. Amino acids and peptides. XXVIII. Synthesis of peptide fragments related to eglin c and studies on the relationship between their structure and effects on human leukocyte elastase, cathepsin G and alpha-chymotrypsin Chem Pharm Bull (Tokyo). 1990 Sep;38(9):2369-76._x000D_ 2: Hu H, Clarkson MW, Hermans J, Lee AL. Increased rigidity of eglin c at acidic pH: evidence from NMR spin relaxation and MD simulations Biochemistry. 2003 Dec 2;42(47):13856-68._x000D_ 3: Tsuboi S, Takeda M, Okada Y, Nagamatsu Y, Yamamoto J. Amino acids and peptides. XXX. Synthesis of eglin c (41-49) and eglin c (60-63) and examination of their inhibitory activity towards human leukocyte elastase, cathepsin G, porcine pancreatic elastase and alpha-chymotrypsin Chem Pharm Bull (Tokyo). 1991 Jan;39(1):184-6._x000D_ 4: Hyberts SG, Märki W, Wagner G. Stereospecific assignments of side-chain protons and characterization of torsion angles in Eglin c Eur J Biochem. 1987 May 4;164(3):625-35._x000D_ 5: Glusa E, Adam C. Endothelium-dependent relaxation induced by cathepsin G in porcine pulmonary arteries Br J Pharmacol. 2001 Jun;133(3):422-8._x000D_ 6: Hu H, Hermans J, Lee AL. Relating side-chain mobility in proteins to rotameric transitions: insights from molecular dynamics simulations and NMR J Biomol NMR. 2005 Jun;32(2):151-62._x000D_ 7: Clarkson MW, Gilmore SA, Edgell MH, Lee AL. Dynamic coupling and allosteric behavior in a nonallosteric protein Biochemistry. 2006 Jun 27;45(25):7693-9._x000D_ 8: Tate S, Ohno A, Seeram SS, Hiraga K, Oda K, Kainosho M. Elucidation of the mode of interaction of thermolysin with a proteinaceous metalloproteinase inhibitor, SMPI, based on a model complex structure and a structural dynamics analysis J Mol Biol. 1998 Sep 18;282(2):435-46._x000D_ 9: Yamaguchi T, Kido H, Fukase M, Fujita T, Katunuma N. A membrane-bound metallo-endopeptidase from rat kidney hydrolyzing parathyroid hormone. Purification and characterization Eur J Biochem. 1991 Sep 1;200(2):563-71._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/7558600">10: Brandt W, Lehmann T, Willkomm C, Fittkau S, Barth A. CoMFA investigations on two series of artificial peptide inhibitors of the serine protease thermitase. Synthesis of an inhibitor of predicted greater potency Int J Pept Protein Res. 1995 Jul;46(1):73-8. </a>_x000D_ _x000D_ <strong>Products Related to Eglin c (60-63)-methyl ester can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>