PFKFB4 Protein

<strong>PFKFB4 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2014570_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 82¬†kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> ‚àí20¬∞C_x000D_ <strong>Keywords:</strong> PFKFB4 Protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lu C, Qiao P, Fu R, Wang Y, Lu J, Ling X, Liu L, Sun Y, Ren C, Yu Z. Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis Cell Death Dis. 2022 Sep 15;13(9):790._x000D_ 2: Dasgupta S, Rajapakshe K, Zhu B, Nikolai BC, Yi P, Putluri N, Choi JM, Jung SY, Coarfa C, Westbrook TF, Zhang XH, Foulds CE, Tsai SY, Tsai MJ, O'Malley BW. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer Nature. 2018 Apr;556(7700):249-254._x000D_ 3: Gao R, Li D, Xun J, Zhou W, Li J, Wang J, Liu C, Li X, Shen W, Qiao H, Stupack DG, Luo N. CD44ICD promotes breast cancer stemness via PFKFB4-mediated glucose metabolism Theranostics. 2018 Nov 29;8(22):6248-6262._x000D_ 4: Feng C, Li Y, Li K, Lyu Y, Zhu W, Jiang H, Wen H. PFKFB4 is overexpressed in clear-cell renal cell carcinoma promoting pentose phosphate pathway that mediates Sunitinib resistance J Exp Clin Cancer Res. 2021 Sep 30;40(1):308._x000D_ 5: Wang S, Bei Y, Tian Q, He J, Wang R, Wang Q, Sun L, Ke J, Xie C, Shen P. PFKFB4 facilitates palbociclib resistance in oestrogen receptor-positive breast cancer by enhancing stemness Cell Prolif. 2023 Jan;56(1):e13337._x000D_ 6: Kotowski K, Rosik J, Machaj F, Supplitt S, Wiczew D, Jab≈Ço≈Ñska K, Wiechec E, Ghavami S, Dziƒôgiel P. Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic Targets Cancers (Basel). 2021 Feb 22;13(4):909._x000D_ 7: Phillips E, Balss J, Bethke F, Pusch S, Christen S, Hielscher T, Schn√∂lzer M, Fletcher MNC, Habel A, Tessmer C, Brenner LM, G√∂ttmann M, Capper D, Herold-Mende C, von Deimling A, Fendt SM, Goidts V. PFKFB4 interacts with FBXO28 to promote HIF-1Œ± signaling in glioblastoma Oncogenesis. 2022 Sep 17;11(1):57._x000D_ 8: Meng J, Chen X, Han Z. PFKFB4 promotes lung adenocarcinoma progression via phosphorylating and activating transcriptional coactivator SRC-2 BMC Pulm Med. 2021 Feb 16;21(1):60._x000D_ 9: Wang F, Wu X, Li Y, Cao X, Zhang C, Gao Y. PFKFB4 as a promising biomarker to predict a poor prognosis in patients with gastric cancer Oncol Lett. 2021 Apr;21(4):296._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30415245">10: Gao R, Liu Y, Li D, Xun J, Zhou W, Wang P, Liu C, Li X, Shen W, Su W, Qiao H, Stupack DG, Luo N. PFKFB4 Promotes Breast Cancer Metastasis via Induction of Hyaluronan Production in a p38-Dependent Manner Cell Physiol Biochem. 2018;50(6):2108-2123. </a>_x000D_ _x000D_ <strong>Products Related to PFKFB4 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>