Purpurin 18

Purpurin 18, a derivative of chlorophyll and a type of dihydroporphyrin, is used to produce photosensitizers. Purpurin 18 photodynamic therapy can induce cell apoptosis and has anti-tumor activity[1][2].

Product Specifications

CAS Number

[25465-77-4]

UNSPSC

12352005

Target

Apoptosis; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/purpurin-18.html

Concentration

10mM

Purity

95.0

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : < 1 mg/mL

Smiles

O=C(O1)/C2=C([C@H]3CCC(O)=O)/N=C([C@H]3C)/C=C(C(C)=C/4C=C)\NC4=C/C5=N/C(C(CC)=C5C)=C\C6=C(C)C(C1=O)=C2N6

Molecular Formula

C33H32N4O5

Molecular Weight

564.63

References & Citations

[1]NicolasDrogat, et al. High yield preparation of purpurin-18 from Spirulina maxima. Dyes and Pigments|[2]Pengyun Huang, et al. Photodynamic treatment with purpurin 18 effectively inhibits triple negative breast cancer by inducing cell apoptosis. Lasers Med Sci. 2021 Mar;36 (2) :339-347.