Trefoil Factor-3 (Human Recombinant)

<strong>Human Trefoil Factor-3</strong>_x000D_ <strong>Catalog number:</strong> B2010371_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Human Trefoil Factor-3 expressed in E. coli. This protein acts as a regulatory peptide involved in mucosal protection and repair in the gastrointestinal tract._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuTFF-3; ITF; TFI_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Griffin BR, Faubel S, Edelstein CL. Biomarkers of Drug-Induced Kidney_x000D_ Toxicity. Ther Drug Monit. 2019 Apr;41(2):213-226._x000D_ _x000D_ 2: Popp J, Schicht M, Garreis F, Klinger P, Gelse K, Sesselmann S, Tsokos M,_x000D_ Etzold S, Stiller D, Claassen H, Paulsen F. Human Synovia Contains Trefoil_x000D_ Factor Family (TFF) Peptides 1-3 Although Synovial Membrane Only Produces TFF3:_x000D_ Implications in Osteoarthritis and Rheumatoid Arthritis. Int J Mol Sci. 2019 Dec_x000D_ 3;20(23):6105._x000D_ _x000D_ 3: Fitzgerald RC, di Pietro M, O'Donovan M, Maroni R, Muldrew B, Debiram-Beecham_x000D_ I, Gehrung M, Offman J, Tripathi M, Smith SG, Aigret B, Walter FM, Rubin G;_x000D_ BEST3 Trial team, Sasieni P. Cytosponge-trefoil factor 3 versus usual care to_x000D_ identify Barrett's oesophagus in a primary care setting: a multicentre,_x000D_ pragmatic, randomised controlled trial. Lancet. 2020 Aug 1;396(10247):333-344._x000D_ _x000D_ 4: Krüger K, Schmid S, Paulsen F, Ignatius A, Klinger P, Hotfiel T, Swoboda B,_x000D_ Gelse K. Trefoil Factor 3 (TFF3) Is Involved in Cell Migration for Skeletal_x000D_ Repair. Int J Mol Sci. 2019 Sep 1;20(17):4277._x000D_ _x000D_ 5: Sun Y, Wang L, Zhou Y, Mao X, Deng X. Human Trefoil Factor 3 induces the_x000D_ transcription of its own promoter through STAT3. Sci Rep. 2016 Jul 25;6:30421._x000D_ _x000D_ 6: Li Q, Wang K, Su C, Fang J. Serum Trefoil Factor 3 as a Protein Biomarker for_x000D_ the Diagnosis of Colorectal Cancer. Technol Cancer Res Treat. 2017_x000D_ Aug;16(4):440-445._x000D_ _x000D_ 7: Zhang Z. Trefoil factor 3 knock-down prevents autophagy-related gene 12_x000D_ elevation in colon adenocarcinoma. J Histotechnol. 2019 Dec;42(4):169-176._x000D_ _x000D_ 8: Nakov R, Velikova T, Nakov V, Gerova V, Tankova L. Trefoil Factor 3 is Highly_x000D_ Predictive of Complete Mucosal Healing Independently and in Combination with_x000D_ C-Reactive Protein in Patients with Ulcerative Colitis. J Gastrointestin Liver_x000D_ Dis. 2019 Jun 1;28:169-174._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32630599/">_x000D_ 9: Hoffmann W. Trefoil Factor Family (TFF) Peptides and Their Diverse Molecular_x000D_ Functions in Mucus Barrier Protection and More: Changing the Paradigm. Int J Mol_x000D_ Sci. 2020 Jun 25;21(12):4535. </a>_x000D_ _x000D_ <strong>Products Related to Human Trefoil Factor-3 </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>