Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PROTAC K-Ras Degrader-3

PROTAC K-Ras Degrader-3 (compound 40) is a PROTAC degrader of K-Ras with a DC50 of ≤ 1 nM against SW620 KRAS G12D, and a GI50 of ≤ 10 nM against SW620 3D cell growth. PROTAC K-Ras Degrader-3 can be utilized in cancer research[1].

Product Specifications

CAS Number

3043670-68-1

UNSPSC

12352005

Target

PROTACs; Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-k-ras-degrader-3.html

Purity

98.08

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC1=C(CC)C2=C(C3=C(F)C4=NC(OCC5(CC5)CN6CCC(CN7CC8(CCN(C9=CC=C(C(N([C@@H]%10C(NC(CC%10)=O)=O)C%11)=O)C%11=C9)CC8)C7)(C)CC6)=NC(N%12C[C@@](O)(C)CCC%12)=C4C=N3)C=C(O)C=C2C=C1

Molecular Formula

C57H67F2N9O6

Molecular Weight

1012.20

References & Citations

[1]Robert L, et al. Glutarimide-containing pan-kras-mutant degrader compounds and uses thereof, WO2024118966A1, 2024-06-06

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

p53 (TP53) Mouse Monoclonal Antibody [Clone ID: OTIpab 240]
CF808657 100 µg

p53 (TP53) Mouse Monoclonal Antibody [Clone ID: OTIpab 240]

Sign In for Pricing
View Details
Tmem190 Mouse Gene Knockout Kit (CRISPR)
KN517779 1 Kit

Tmem190 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
CD56 / NCAM (123C3.D5), CF640R conjugate, 0.1mg/mL
BNC400015-100 1x 100 µL

CD56 / NCAM (123C3.D5), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
9530002B09Rik Mouse Gene Knockout Kit (CRISPR)
KN500524 1 Kit

9530002B09Rik Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
C22orf15 Human Gene Knockout Kit (CRISPR)
KN420934 1 Kit

C22orf15 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Ibudilast-d3 (Major)
TRC-I125002-1MG 1 mg

Ibudilast-d3 (Major)

Sign In for Pricing
View Details