Pyr3
Product Specifications
UNSPSC Description
Pyr3 is a selective inhibitor of transient receptor potential canonical channel 3 (TRPC3), with an IC50 of 700 nM for TRPC3-mediated Ca2+ influx.
Target Antigen
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Pyr3.html
Purity
99.90
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(C1=C(C(F)(F)F)N(C2=CC=C(NC(/C(Cl)=C(Cl)/Cl)=O)C=C2)N=C1)OCC
Molecular Weight
456.63
References & Citations
[1]Kiyonaka S, et al. Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5400-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108465/Pyr3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108465/Pyr3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1160514-60-2
Available Sizes
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