17-Phenyl-18,19,20-trinor-PGD2

17-Phenyl-18,19,20-trinor-PGD2 (17-Phenyl-PGD2) is an analogue of prostaglandin D2 (PGD2; HY-101988) . 17-Phenyl-18,19,20-trinor-PGD2 is a potent inhibitor of platelet aggregation caused by aenosine diphosphate (ADP), with the IC50 of 8.4 μM (PGD2 IC50 = 18.6 nM) . 17-Phenyl-18,19,20-trinor-PGD2 is a weak agonist of cyclic AMP accumulation[1].

Product Specifications

CAS Number

[85280-91-7]

Product Name Alternative

17-Phenyl-PGD2

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/17-phenyl-18-19-20-trinor-pgd2.html

Solubility

10 mM in DMSO

Smiles

OC(CCC/C=C\C[C@@H]1[C@H](C(C[C@@H]1O)=O)/C=C/[C@@H](O)CCC2=CC=CC=C2)=O

Molecular Formula

C23H30O5

Molecular Weight

386.48

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]S Narumiya, et al. Different responsiveness of prostaglandin D2-sensitive systems to prostaglandin D2 and its analogues. Br J Pharmacol. 1985 Jun;85 (2) :367-75.