SJB3-019A
Product Specifications
UNSPSC Description
SJB3-019A is a potent and novel USP1 inhibitor, 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells with IC50 of 0.0781 μM.
Target Antigen
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SJB3-019A.html
Purity
99.68
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C1C2=C(OC(C3=CC=CN=C3)=N2)C(C4=CC=CC=C41)=O
Molecular Weight
276.25
References & Citations
[1]Helena Mistry, et al. Small molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther Published OnlineFirst October 15, 2013.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-80012/SJB3-019A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-80012/SJB3-019A-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2070015-29-9
Available Sizes
Curated Selection
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