p21 Recombinant Rabbit Monoclonal Antibody [JE00-63]
p21Cip1 (alternatively p21Waf1), also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that is capable of inhibiting all cyclin/CDK complexes, though is primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest. This protein is encoded by the CDKN1A gene located on chromosome 6 (6p21.2) in humans.
Product Specifications
Product Name Alternative
Abbreviation
CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1
Swiss Prot
P38936 Human
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within
Isotype
IgG
Clone
JE00-63
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, IP
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:50 ;IP: 1-2μg/sample
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 18 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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