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p21 Recombinant Rabbit Monoclonal Antibody [JE00-63]

p21Cip1 (alternatively p21Waf1), also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that is capable of inhibiting all cyclin/CDK complexes, though is primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest. This protein is encoded by the CDKN1A gene located on chromosome 6 (6p21.2) in humans.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

CAP20 antibody CDK-interacting protein 1 antibody CDKI antibody CDKN1 antibody Cdkn1a antibody CDN1A_HUMAN antibody CIP1 antibody Cyclin Dependent Kinase Inhibitor 1A antibody Cyclin-dependent kinase inhibitor 1 antibody Cyclin-dependent kinase inhibitor 1A (P21) antibody Cyclin-dependent kinase inhibitor 1A (p21, Cip1) antibody DNA Synthesis Inhibitor antibody MDA-6 antibody MDA6 antibody Melanoma differentiation-associated protein 6 antibody Melanoma differentiation-associated protein antibody p21 antibody P21 protein antibody p21CIP1 antibody p21Cip1/Waf1 antibody p21WAF antibody PIC1 antibody SDI1 antibody SLC12A9 antibody WAF1 antibody Wild type p53 activated fragment 1 (WAF1) antibody Wild type p53 activated fragment 1 antibody Wildtype p53-activated fragment 1 antibody

Abbreviation

CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1

Swiss Prot

P38936 Human

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within

Isotype

IgG

Clone

JE00-63

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, IP

Positive Control

HeLa cell lysate, HUVEC cell lysate, MCF7 cell lysate, HCT 116 cell lysate, A549 cell lysate, LNCaP cell lysate, 293T cell lysate, MCF7, human breast cancer tissue, human cervical cancer tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:50 ;IP: 1-2μg/sample

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 18 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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