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Iso-​H7 (dihydrochloride)

Iso-​H7 dihydrochloride is an inhibitor of protein kinase with IC50 values of 22 and 34 μM to PKC and PKA respectively. Iso-H7 dihydrochloride has negative control of PKA on satellite cell myogenesis[1].

Product Specifications

CAS Number

140663-38-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PKA; PKC

Type

Reference compound

Related Pathways

Epigenetics; Stem Cell/Wnt; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/iso-h7-dihydrochloride.html

Concentration

10mM

Purity

99.06

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O=S(C1=CC=CC2=C1C=CN=C2)(N3CC(C)NCC3)=O.[H]Cl.[H]Cl

Molecular Formula

C14H19Cl2N3O2S

Molecular Weight

364.29

Precautions

H302, H315, H319, H335

References & Citations

[1]C Lagord, et al. Satellite cell myogenesis is highly stimulated by the kinase inhibitor iso-H7: comparison with HA1004 and staurosporine effects. Biochem Biophys Res Commun. 1993, 191, 3.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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