Iso-H7 (dihydrochloride)
Iso-H7 dihydrochloride is an inhibitor of protein kinase with IC50 values of 22 and 34 μM to PKC and PKA respectively. Iso-H7 dihydrochloride has negative control of PKA on satellite cell myogenesis[1].
Product Specifications
CAS Number
140663-38-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PKA; PKC
Type
Reference compound
Related Pathways
Epigenetics; Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/iso-h7-dihydrochloride.html
Concentration
10mM
Purity
99.06
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=S(C1=CC=CC2=C1C=CN=C2)(N3CC(C)NCC3)=O.[H]Cl.[H]Cl
Molecular Formula
C14H19Cl2N3O2S
Molecular Weight
364.29
Precautions
H302, H315, H319, H335
References & Citations
[1]C Lagord, et al. Satellite cell myogenesis is highly stimulated by the kinase inhibitor iso-H7: comparison with HA1004 and staurosporine effects. Biochem Biophys Res Commun. 1993, 191, 3.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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