Fmoc-NH-PEG1-CH2COOH
Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fmoc-NH-PEG1-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[260367-12-2]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-nh-peg1-ch2cooh.html
Purity
99.91
Solubility
10 mM in DMSO
Smiles
O=C(O)COCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Molecular Formula
C19H19NO5
Molecular Weight
341.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Lorenzo Benatuil, et al. Anti-cd98 antibodies and antibody drug conjugates. WO2017214456A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MGAT3, CT (MGAT3, GGNT3, Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III) (MaxLight 650)
MGAT3, CT (MGAT3, GGNT3, Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III) (MaxLight 650)
SUPV3L1 (ATP-dependent RNA Helicase SUPV3L1, Mitochondrial, Suppressor of Var1 3-like Protein 1, SUV3-like Protein 1, SUV3)