Fmoc-NH-PEG1-CH2COOH
Product Specifications
UNSPSC Description
Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG1-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-nh-peg1-ch2cooh.html
Purity
99.91
Solubility
10 mM in DMSO
Smiles
O=C(O)COCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Molecular Weight
341.363
References & Citations
[1]Lorenzo Benatuil, et al. Anti-cd98 antibodies and antibody drug conjugates. WO2017214456A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W055861/Fmoc-NH-PEG1-CH2COOH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W055861/Fmoc-NH-PEG1-CH2COOH-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
260367-12-2
Available Sizes
Curated Selection
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