Fmoc-NH-PEG1-CH2COOH
Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fmoc-NH-PEG1-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[260367-12-2]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-nh-peg1-ch2cooh.html
Purity
99.91
Solubility
10 mM in DMSO
Smiles
O=C(O)COCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Molecular Formula
C19H19NO5
Molecular Weight
341.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Lorenzo Benatuil, et al. Anti-cd98 antibodies and antibody drug conjugates. WO2017214456A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Human Interleukin 18 Receptor Accessory Protein (IL18RAP) Antibody Pair Kit (with Standard)
Human Interleukin 18 Receptor Accessory Protein (IL18RAP) Antibody Pair Kit (with Standard)
Human Interleukin 18 Receptor Accessory Protein (IL18RAP) Antibody Pair Kit (with Standard)
Human Interleukin 18 Receptor Accessory Protein (IL18RAP) Antibody Pair Kit (with Standard)
FKBP8, ID (FKBP8, FKBP38, Peptidyl-prolyl cis-trans isomerase FKBP8, 38kD FK506-binding protein, FK506-binding protein 8, FKBPR38, Rotamase) (Azide free) (HRP)