Indusatumab vedotin Antibody
Indusatumab vedotin (MLN-0264) is an anti-GCC antibody-drug conjugate (ADC) delivering monomethyl auristatin E. It exhibits anti-tumor activity by inducing G2/M cell cycle arrest and apoptosis, as demonstrated in pancreatic cancer cell line studies. Its mechanism has also been explored in in vivo models of gastrointestinal cancers.
Product Specifications
Target
Antibody-Drug Conjugates (ADCs), Guanylate cyclase
Conjugation
Unconjugated
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Concentration
12.85 mg/mL
Purity
95.00% (May vary between batches)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
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